Chronic Fatigue, Low Energy, and Brain Fog | An Integrative Nurse Practitioner’s Step-by-Step Blueprint

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Why are you so tired, even when you're doing everything "right"?

In this solo episode of The Inner Script, Stephanie Baubie, NP walks you through the exact blueprint she uses in practice to evaluate chronic fatigue, low energy, and brain fog — from the history she takes in the exam room to the blood tests she orders and the treatment plan she builds from there. Instead of jumping straight to supplements or expensive testing, Stephanie breaks down a stepwise, root-cause approach that starts with sleep, cortisol, movement, diet, hormones, and stress before a single lab is ever drawn.

Fatigue is rarely caused by one thing. It's layered — sleep quality, cortisol patterns, overtraining, under-fueling, menstrual cycle irregularities, digestion, and chronic stress can all be quietly driving low energy and brain fog at the same time. Stephanie explains how she distinguishes a high-cortisol "wired but tired" pattern from a low-cortisol, constantly-drained pattern, why waking between 1 and 3 a.m. can be a clue, and why overtraining especially HIIT and heated workouts is a surprisingly common culprit in women.

From there, she walks through the foundational blood work she orders for almost every fatigued patient, the additional labs she adds based on symptoms, and why she's cautious about ordering a single morning cortisol test. She also shares practical, back-to-basics treatment principles around sleep support, caffeine and alcohol, acupuncture, and movement that patients can start using right away, while waiting on labs.

If you've ever wondered why you feel exhausted no matter how much you sleep, or you suspect your cortisol, hormones, or nervous system might be playing a role, this episode gives you the exact framework to bring back to your own healthcare provider.

This episode is for you if…

  • You feel tired no matter how much you sleep, or you never wake up feeling rested.

  • You suspect your cortisol, hormones, or nervous system may be playing a role in your fatigue.

  • You want a root-cause, integrative approach to chronic fatigue and brain fog — including exactly which labs to ask for.


Episode Timestamps

00:00 Understanding Chronic Fatigue and Its Nuances
02:28 The Importance of Sleep in Energy Levels
04:48 Exercise and Its Impact on Fatigue
07:24 Dietary Considerations for Energy
09:35 The Role of Hormones and Menstrual Health
11:54 Digestion and Detoxification
14:16 The Overlooked Factor: Stress Management
16:31 Lab Testing and Diagnostics
18:44 Treatment Protocols for Chronic Fatigue
21:25 Real-Life Case Studies and Patient Insights


Resources & Mentions

Curious about a supplement Steph has mentioned in the episode?

If you’re looking for products Steph personally recommends in practice, you can browse her dispensary here: Stephanie’s Fullscript dispensary

Please consult your healthcare provider before starting any new supplement. Food, lifestyle, and nervous system support always come first.


Free Guide: Strategic Blood Tests for Chronic Fatigue

This companion guide walks you through exactly which blood tests to ask for when evaluating chronic fatigue, low energy, and brain fog plus why each one matters so you can bring it straight to your own healthcare provider. Download it here: Patreon companion resource

You can also join Steph’s free Patreon community here:
The Inner Script Patreon


Stephanie Baubie, NP, smiling sitting on a dark green couch. She's wearing an Oura ring, a simple gold necklace, and her blond hair is long and straight.

Meet Your Host: Stephanie Baubie, NP

Stephanie Baubie is an integrative nurse practitioner and the host of The Inner Script Podcast, where she explores the deeper stories behind health, healing, identity, and transformation. Through a blend of functional medicine, nervous system awareness, emotional insight, and honest conversation, Stephanie helps women better understand their bodies while questioning the narratives they’ve inherited about wellness, worth, and what it means to truly feel well.

On The Inner Script, Stephanie sits down with physicians, founders, thought leaders, and experts in women’s health, while also sharing solo reflections on the transitions and inner shifts that shape our lives.

Follow Steph on Instagram.


FAQs

What blood tests should I ask for if I have chronic fatigue?

In this episode of The Inner Script, Stephanie Baubie explains that she typically starts with foundational labs for almost everyone dealing with chronic fatigue: a complete blood count, comprehensive metabolic panel, full thyroid panel with antibodies, hemoglobin A1C, vitamin B12 and folate, vitamin D, and an iron panel with ferritin. She then adds labs like fasting insulin, DHEA-S, or a female hormone panel based on the person's individual symptoms.

What are the signs of high cortisol versus low cortisol?

Stephanie Baubie describes a high-cortisol, "wired but tired" pattern as trouble falling or staying asleep, often with waking consistently between 1 and 3 a.m. A low-cortisol pattern tends to look like constant tiredness even after 10 to 12 hours of sleep, with a person still never feeling rested. She explains that identifying which pattern is present helps guide the rest of the workup.

Can overtraining cause chronic fatigue in women?

Yes. On The Inner Script, Stephanie Baubie discusses how overtraining, particularly frequent high-intensity interval training or workouts done in heated rooms, can contribute to cortisol dysregulation and chronic fatigue in women. She looks for signs like feeling great during a workout but crashing one to two hours afterward as a clue that someone needs more recovery days.

Why does low ferritin cause fatigue and hair loss even when hemoglobin looks normal?

Stephanie Baubie explains that ferritin reflects the body's stored iron, while hemoglobin only reflects circulating iron, so a person can have "normal" hemoglobin with critically low iron stores. She notes this is an extremely common and often missed cause of fatigue and hair loss in women, which is why she checks a full iron panel with ferritin rather than iron levels alone.

Is a single cortisol blood test useful for diagnosing adrenal issues?

Generally, no. In this episode, Stephanie Baubie explains that a single morning serum cortisol test does not capture how cortisol rises and falls throughout the day, so it's not particularly useful for evaluating everyday cortisol dysregulation. She reserves cortisol testing and endocrinology referral for cases where a more severe adrenal disorder, like Addison's disease or Cushing's syndrome, is suspected.

How is chronic stress connected to low energy and brain fog?

Stephanie Baubie considers stress to be one of the most overlooked drivers of chronic fatigue. She explains that showing up daily to a job, relationship, or environment that feels misaligned keeps the body in a fight-or-flight state, which raises cortisol and heart rate and makes it very difficult to resolve fatigue until the underlying stress is addressed.

What at-home tests can help evaluate hormones and energy levels?

For people who want more comprehensive insight beyond standard bloodwork, Stephanie Baubie mentions the DUTCH test, which measures detailed hormone metabolites and cortisol patterns through dried urine, as well as the Mira hormone monitor and Function Health for more extensive biomarker testing over time.

Disclaimer

Everything shared in this episode is for educational purposes and personal reflection only. It is not medical advice. Always work with your own healthcare provider for individual care.

We sometimes include links to products and services we find interesting. These may or may not be affiliate links. Thanks for your support.

Podcast production by Jamie Brooke.

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